PhD Student ‒ Cell Biology and Immunology
The Fraunhofer branch »Translational Neuroinflammation and Automated Microscopy« in Göttingen is part of the Fraunhofer Institute for Translational Medicine and Pharmacology ITMP. Here, we focus on understanding pathological and immunological mechanisms in the development and progression of demyelinating diseases of the central nervous system.
Multiple Sclerosis is an inflammatory demyelinating disease of the central nervous system. For relapsing-remitting multiple sclerosis, major advances have been made in the development of various disease-modifying therapies that effectively reduce the number and severity of new relapses as well as MRI activity. During the progressive stages of multiple sclerosis, in which new lesions become less frequent and the progression is characterized by a steady increase in neurological disability, most of the drugs on the market are unable to prevent disease progression.
The aim of this study is to test suitable candidates for the treatment of progressive multiple sclerosis via animal models and in vitro analysis. For in vivo experiments, we will utilize the murine multiple sclerosis model for experimental autoimmune encephalomyelitis as well as the cuprizone-induced model of demyelination. For in vitro experiments, primary cell cultures of CNS-resident cells will be used. The main methods of this study will be among others flow cytometry, magnetic-activated cell sorting, ELISA, qPCR and immunohistology.
What you will do
PhD students have the opportunity to participate in one of several PhD programs in collaboration with the University of Göttingen, where they will be able to present their work at conferences and publish their work in scientific journals. Through this close cooperation, participants have access to a wide range of techniques and facilities.
What you bring to the table
Highly motivated and have a strong interest to work at the interface between research, medicine, and industry. PhD-students furthermore: Your professional qualifications are complemented by a quick grasp, structured and independent way of working and a good team spirit.
What you can expect
The weekly working time is 39 hours. This position is also available on a part-time basis. We value and promote the diversity of our employees' skills and therefore welcome all applications - regardless of age, gender, nationality, ethnic and social origin, religion, ideology, disability, sexual orientation and identity. Severely disabled persons are given preference in the event of equal suitability. Appointment, remuneration and social security benefits based on the public-sector collective wage agreement (TVöD).
With its focus on developing key technologies that are vital for the future and enabling the commercial utilization of this work by business and industry, Fraunhofer plays a central role in the innovation process. As a pioneer and catalyst for groundbreaking developments and scientific excellence, Fraunhofer helps shape society now and in the future.
Interested? Apply online now. We look forward to getting to know you!
Questions to Position: If you have any questions about the application process, please contact Dr. Ursula Wegenka
Prof. Martin Weber / Dr. Darius Häusler
Phone +49 551 39-63658
ursula.wegenka@itmp.fraunhofer.de
Phone +49 551 39-65284
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
Requisition Number: 72711
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Biology, Molecular Biology, Cytology, Cell Biology, Part Time, Science, Healthcare