City:  Straubing
Date:  Nov 25, 2023

Master's thesis to develop efficient genetic tools for methylotrophic bacteria in Straubing

The Fraunhofer-Gesellschaft ( currently operates 76 institutes and research institutions throughout Germany and is the world’s leading applied research organization. Around 30 000 employees work with an annual research budget of 2.9 billion euros. 


At the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, we combine biology and technology across competencies in our business areas of Health, Sustainable Chemistry, and Environment. For more than 70 years, we have been developing processes, technologies, and products and successfully bringing them to industrial application. We conduct research at our sites in Stuttgart, Leuna, and Straubing in close cooperation with numerous universities and research institutes in Germany and abroad.


We offer you the opportunity to get hands on an exciting project in the framework of your master´s thesis. The projekt targets to enhance the genetic engineering toolbox for metabolic engineering of the methylotrophic micorbe Methylorubrum extorquens.



Suitable for students majoring in biochemistry, biotechnology, technical biology, systems biotechnology, and bioprocess engineering.


What you will do


  • Development of genetic tools for efficient protein expression in Methylorubrum extorquens
  • Development of modern tools for genome-editing of Methylorubrum extorquens
  • Preparation of culture medium and buffers
  • Cultivation of microorganisms (Escherichia coli and Methylorubrum extorquens)
  • Scientific literature research to reveal state-of-the-art
  • Evaluation, discussion and written summary of results
  • Self-reliant and creative work environment


What you bring to the table


  • Experience in molecular biology techniques (e.g. cloning: Golden-Gate, Gibson-Assembly; design of genetic regulatory elements) is required
  • Experience in handling and cultivation of microorganisms is advantageous
  • Suitable for students of the courses Biochemistry, Biotechnology, Technical Biology, Systems Biotechnology and Bioprocess Engineering
  • Participation within a timely project with clearly defined targets
  • Independent working style, creativity, flexibility and ability to work in a team
  • Confident command of the German and English languages, both written and spoken
  • A high degree of initiative and personal responsibility
  • Fun with technical innovations



What you can expect


  • Flexible working hours
  • Cooperation in a collegial and sympathetic team
  • Good working atmosphere, open and friendly interaction with each other
  • Varied activities
  • Versatile opportunities for further training


We offer you an environment that gives you the opportunity to gain a broad spectrum of experience in a short period of time by working on interesting and varied industrial projects with our partners in various industries.

In our teams, creative approaches to solutions are combined with an economic and structured approach.


We value and promote the diversity of our employees' skills and therefore welcome all applications - regardless of age, gender, nationality, ethnic and social origin, religion, ideology, disability, sexual orientation and identity. Severely disabled persons are given preference in the event of equal suitability.


The weekly working time is according to agreement. The position is initially limited to 6 months. Remuneration is based on the general works agreement on the employment of auxiliary staff.



With its focus on developing key technologies that are vital for the future and enabling the commercial utilization of this work by business and industry, Fraunhofer plays a central role in the innovation process. As a pioneer and catalyst for groundbreaking developments and scientific excellence, Fraunhofer helps shape society now and in the future. 


Interested? Apply online now. We look forward to getting to know you!

Questions regarding the application process anwers Mrs. Manuela Göttig-Fickert.

Phone +49 (0)9421/ 9380-1000.


Please apply only by using our Fraunhofer internet portal.

Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB 


Requisition Number: 56825                Application Deadline:


Job Segment: Biology, Molecular Biology, Scientific, Biochemistry, Science, Engineering, Research